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Efficacy of pegfilgrastim and darbepoetin alfa as hematopoietic support for dose-dense every-2-week adjuvant breast cancer chemotherapy.

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After three months of treatment, retinal nerve fibre layer thickness RNFL and macular volumes were significantly higher in people given phenytoin versus placebo, indicating a neuroprotective effect.

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Randomized trial of the cardioprotective agent ICRF-187 in pediatric sarcoma patients treated with doxorubicin.

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Stem cell transplantation and high-dose cyclophosphamide treatment are two such immune-system-based approaches.

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Amico in the American Journal of Medicine (JAMA Sept 2015) demonstrates better survival of patients who were in the intermediate to severe comorbidity groups by undergoing only radiation without additional concurrent hormonal ablation for 6 months.

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When use for biopsy proven "minimal change" nephrotic syndrome in a male child, the incidence of oligospermia and azoospermia increases if the duration of treatment exceeds 60 days.

4 There are a number of reasons for this increase, including fixed obstruction in the coronary arteries, vasoconstriction, thrombus formation, and platelet aggregation.

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Among these patients, the incidence of cardiac dysfunction of New York Heart Association class III or IV was highest among patients who had received an anthracycline, cyclophosphamide, and trastuzumab (16 percent, as compared with 3 percent among patients who had received an anthracycline and cyclophosphamide alone, 2 percent among those who had received paclitaxel and trastuzumab, and 1 percent among those who had received paclitaxel alone).

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Separate analyses were undertaken for patients receiving myeloablative and reduced-intensity transplantations.

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Between 2005 and 2006, we conducted a multicenter, single-arm, open-label first-in-man study at six study sites in three European countries in accordance with the Declaration of Helsinki, current International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) guidelines and all applicable regulatory and ethical requirements.

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When cyclophosphamide is the accepted standard of care (renal and neurologic), the maximally tolerated dose of prednisone will be sufficient to meet the corticosteroid criterion.

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