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However, standard antidepressants are commonly used as adjuncts to mood-stabilizing medication for the treatment of bipolar depression, despite limited evidence of the short-term and long-term efficacies and the putative risk of treatment-emergent mania or hypomania.

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Skip the missed dose if it is almost time for your next scheduled dose.

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And if they do develop tremors or other movement problems, he said, they should not brush it off.

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Dose reductions or discontinuation of valproate should be considered in patients with decreased food or fluid intake and in patients with excessive somnolence.

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Discontinue drug if multiorgan hypersensitivity reaction occurs.

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In the regulatory trials, 100 mg was the optimal dose for prevention.

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Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect.

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