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Infectious agents such as Mycobacterium paratuberculosis, Pseudomonas species, and Listeria species have all been implicated in the pathogenesis of Crohn disease, suggesting that the inflammation seen with the disease is the result of a dysfunctional, but appropriate, response to an infectious source.

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There are no specific guidelines regarding management of CRMO and IBD, but general consensus at this time seems to be that for most patients controlling the bowel disease leads to control of the CRMO.

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Ulcerative colitis tends to run in families, with up to 20% of patients having a close relative who also has the disease.

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She thinks that the change in her diet and eating white rice is causing greater discomfort.

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Some patients with ulcerative colitis also demonstrate inflammatory changes in the terminal ileum (ileitis), but these findings lack the skip pattern that is characteristic of Crohn disease.

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