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Led by Sonja A. Swanson, of the National Institute of Mental Health, the research team reported the findings online March 7 in the Archives of General Psychiatry.

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If corticotropin (ACTH) is administered for treatment of an attack of gouty arthritis, it is recommended that colchicine also be given in doses of at least 1 mg per day, and that the latter be continued for a few days after the is withdrawn.

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After gout flares have resolved, there are medications that can lower the level of uric acid over time in order to prevent or lessen attacks.

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Colchicine plus conventional therapy led to a clinically important and statistically significant benefit over conventional treatment, decreasing the recurrence rate in patients with a first episode of acute pericarditis.

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The possibility of such an exclusivity period arose because colchicine, despite its longevity, had never been officially approved by the FDA for a particular indication.

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Colchicine prophylaxis for 6 months, one or two tabs daily, is generally given when uric acid-lowering therapy is begun.

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