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I would like to share my opinion concerning Hydrea, I hope it would be useful to someone who still haven't found an effective medication or is not sure about the choice. I have been on this medication (1 capsule a day) since the year 2010. I was diagnosed with Myeloperliferative Disease about 7 years ago and since that time I have tried several medications that were supposed to bring my platelets and hemoglobin levels down. And to be honest some of other cancer meds were more or less effective, but I inevitably had to stop the treatment courses and ask my doctor to switch me to another med because of the side effects I couldn't tolerate. Most awful side effects were unbearable pain in my muscles and bones that would keep me awake for many nights on end. I also had nausea and fatigue that would keep me away from my usual duties. I do have a serious illness but I want to stay active and to live my life the way I am used to. And when medications produce some effect but make me suffer and forget about normal life, then these meds are not for me. With Hydrea everything is quite different. I have side effects but they are not that serious for me to stop treatment. Besides the drug is really good for its purpose. So, while looking for something more effective or better to say while waiting for the pharmacists to create a new med, I am more than ok with Hydrea.



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I've had brutal neurological side effects that have been decreasing slowly with time. Nevertheless, Hydrea compared to Anagrelid and Interferon is by far the medicine I tolerate better.

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Activity changes: avoidance of cold Smoking cessation (if appropriate) Surgery (used in fewer than one-quarter ofclients): sympathectomyDrug therapy Calcium channel blockers: diltiazem (Cardizem), nifedipine (Procardia) Vasodilator: phenoxybenzamine (Dibenzyline)INTERVENTIONS AND RATIONALES Warn against exposure to the cold.

Men cannot donate sperm, and neither men nor women can donate blood during lenalidomide treatment.

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Dialysis if acute renal failure occurs Surgery to relieve obstruction or correctthe anomaly responsible for obstruction orvesicoureteral reflux Discontinuation of causative drug (TIN)How to survivethe big exam?

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Your doctor may need to change your treatment plan if you use any of the following drugs: chloroquine, methadone, nefazodone, an antibiotic--clarithromycin, moxifloxacin, telithromycin; antifungal medication--itraconazole, ketoconazole, voriconazole; heart rhythm medicine--amiodarone, disopyramide, dronedarone, procainamide, quinidine, sotalol; HIV or AIDS medicine--atazanavir, indinavir, nelfinavir, ritonavir, saquinavir; or medicine to treat a psychiatric disorder--haloperidol, pimozide, thioridazine, ziprasidone.

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Due to potentially severe clinical outcomes for the cutaneous vasculitic ulcers reported in patients with myeloproliferative disease, hydroxyurea should be discontinued if cutaneous vasculitic ulcerations develop and alternative cytoreductive agents should be initiated as indicated.

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Nerve damage may be caused by HIV itself, by opportunistic infections (OIs) such as cytomegalovirus (CMV), or as a side effect of certain anti-HIV drugs, notably ddI (Videx), ddC (Hivid), and d4T (Zerit).

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PNEUMOTHORAX AND HEMOTHORAXKey signs and symptoms Diminished or absent breath sounds unilaterally Dyspnea, tachypnea, subcutaneous emphysema, cough Sharp pain that increases with exertionKey test results Chest X-ray reveals pneumothorax or hemothorax.

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EatingdisordersBrush up on keyconceptsEating disorders are characterized by severedisturbances in eating behaviors.

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Risperdal), ziprasidone (Geodon)Key interventions Help the client meet basic needs for food, comfort, and a sense of safety.

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Among 60 patients with severe psoriasis treated with hydroxyurea for up to 18 months, 63% had a beneficial response and side effects included marrow suppression, but none had AST elevations or hepatotoxicity; six patients developed fever and an influenza-like syndrome shortly after starting therapy and two redeveloped fever on rechallenge, but liver enzymes remained normal).

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Confusion Decreased ability to relate to others Diminished ability to focus, even withdirection from others Dizziness or light-headedness Edginess, impatience Eyelid twitching Fidgeting or pacing Flushing or pallor Generalized weakness, tremors Increased or decreased blood pressure Insomnia Loss of appetite or revulsion toward food Loss of objectivity Palpitations and tachycardia Physical tension Potential for dangerous, impulsive actions Rapid speech Rapid, shallow breathing or shortness ofbreath Severely impaired rational thought Startle reaction Sudden urge and frequent urination Sweating, itching Trembling Uneasiness and tensionCONTRIBUTING FACTORSDont worry.

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Before receiving therapy, which of thefollowing is required of the client?

Progesterone production ceases until theclients first ovulation.

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