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Does ankylosing spondylitis always show on MRI? Most people with ankylosing spondylitis test positive for HLA-B27, but so do some people who don't have the condition. MRI scans may show the typical changes in your spine and at the sacroiliac joints at an earlier stage of the disease and before changes can be identified on x-rays.
What happens if HLA b27 is positive? A negative result mean you don't have HLA - B27 in your blood. A positive result means HLA - B27 was found in your blood. You may have a higher-than-average risk of certain autoimmune diseases, such as ankylosing spondylitis and reactive arthritis. If it's a common HLA genotype, the child could have many potential fathers.
How is spondylitis diagnosis? There is no specific test to diagnose ankylosing spondylitis, but imaging by X-ray and MRI may show evidence of inflammation of the sacroiliac joint between the sacrum (the triangular bone at the lowest part of the back) and the ilium (the bone felt on the upper part of the hip).

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